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year 27, Issue 2 (ICOP & ICPET 2021 2021)
ICOP & ICPET _ INPC _ ICOFS 2021, 27(2): 29-32 |
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Arefnia F, Zibaii M I, Rezadost H, Dorranian D. Design and fabrication of a flexible and biocompatible polymer optical fiber for optogenetic applications. ICOP & ICPET _ INPC _ ICOFS 2021; 27 (2) :29-32
URL: http://opsi.ir/article-1-2298-en.html
URL: http://opsi.ir/article-1-2298-en.html
1- Laser and Plasma Research Institute, Shahid Beheshti University, Tehran, Plasma Physics Research Center, Science and Research Branch, Islamic Azad University, Tehran
2- Laser and Plasma Research Institute, Shahid Beheshti University, Tehran
3- Medicinal Plants and Drug Research Institute, Shahid Beheshti University, Tehran
4- Plasma Physics Research Center, Science and Research Branch, Islamic Azad University, Tehran
2- Laser and Plasma Research Institute, Shahid Beheshti University, Tehran
3- Medicinal Plants and Drug Research Institute, Shahid Beheshti University, Tehran
4- Plasma Physics Research Center, Science and Research Branch, Islamic Azad University, Tehran
Abstract: (975 Views)
One of the challenges in optogenetic technique is the transmission of light to different areas of brain tissue with minimal damage. In this paper, the design and fabrication of a new type of polymer optical fiber with flexible and degradable biocompatible step-index for the delivery of light with a diameter of 1400 μm and lengths of 3 cm and 7 cm is presented. By coupling the light with the microsphere in to the optical fiber structure, obtained output power efficiency at 532 nm and 650 nm is 64.8% and 11.2%, respectively. Also, the degradation rate of optical fiber constituent polymers poly (octamethylene maleate citrate) and poly (octamethylene citrate) for 8 days is -0.7 s-1 and -0.4 s-1, respectively. The flexibility and degradability of polymer optical fiber Reduces and eliminates the constraints created by fiberglass, including fragility, restricting the animal's free movement, and tissue damage from leaving the tissue.
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