fa Online Monitoring of Gold Nanoparticles by Photothermal Lens Microscopy تخصصی Special پژوهشي Research In this paper, we have developed an inverted photothermal lens microscope with a flow through optical cell to detect the gold nanoparticles (AuNPs) prepared by trisodium citrate reduction. The measurements were made using a continuous-wave excitation (wavelength, 532 nm) and probe laser beams (wavelength, 652 nm).The changes in the transmitted probe beam’s center intensity were detected with a photodiode. The indirect detection of the plasmonic signals of AuNPs was done by using thermal lens phenomena. The results show the possibility of online determination of AuNPs in micro and nano volume in the range of 1.6-6.4 particles per the focal volume of the excitation beam. The irreproducibility of AuNPs’s thermal lens signal in water is eliminated by increasing in the modulation frequency of excitation beam and employing flow optical cell with an optimum flow velocity of sample injection. In this paper, we have developed an inverted photothermal lens microscope with a flow through optical cell to detect the gold nanoparticles (AuNPs) prepared by trisodium citrate reduction. The measurements were made using a continuous-wave excitation (wavelength, 532 nm) and probe laser beams (wavelength, 652 nm).The changes in the transmitted probe beam’s center intensity were detected with a photodiode. The indirect detection of the plasmonic signals of AuNPs was done by using thermal lens phenomena. The results show the possibility of online determination of AuNPs in micro and nano volume in the range of 1.6-6.4 particles per the focal volume of the excitation beam. The irreproducibility of AuNPs’s thermal lens signal in water is eliminated by increasing in the modulation frequency of excitation beam and employing flow optical cell with an optimum flow velocity of sample injection. AuNPs, Inverted Photo Thermal lens Microscope, Online monitoring, Plasmonic AuNPs, Inverted Photo Thermal lens Microscope, Online monitoring, Plasmonic 1667 1670 http://opsi.ir/browse.php?a_code=A-10-1-775&slc_lang=fa&sid=1 Atefeh Abbasi Ahd Atefeh Abbasi Ahd atefeh.abbasiahd@gmail.com 10031947532846003718 10031947532846003718 Yes Chemistry & Chemical Engineering Research Center of Iran (CCERCI) Chemistry & Chemical Engineering Research Center of Iran (CCERCI) kazem kargosha kazem kargosha k.kargosha@ccerci.ac.ir 10031947532846003719 10031947532846003719 No Chemistry & Chemical Engineering Research Center of Iran (CCERCI) Chemistry & Chemical Engineering Research Center of Iran (CCERCI) Sara Madarshahian Sara Madarshahian 10031947532846003720 10031947532846003720 No Chemistry & Chemical Engineering Research Center of Iran (CCERCI) Chemistry & Chemical Engineering Research Center of Iran (CCERCI) Nader Shokoufi Nader Shokoufi shokoufi@yahoo.com 10031947532846003721 10031947532846003721 No Chemistry & Chemical Engineering Research Center of Iran (CCERCI) Chemistry & Chemical Engineering Research Center of Iran (CCERCI)